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Toggle navigation RCSB PDB Deposit Prepare Data PDBx/mmCIF file pdb_extract SF-Tool Ligand Expo MAXIT Validate Data Validation Server Information for Journals Validation Task Forces Deposit Data wwPDB OneDep System PDB-Dev Deposition Help & Resources Deposit FAQ Tutorials Annotation Policies Processing Procedures PDBx/mmCIF Dictionary Chemical Component Dictionary PDB Format Guide BioSync Beamlines/Facilities Related Tools Search Basic Search Advanced Search Sequence Search Unreleased & New Entries Browse Annotations Explore the Archive PDB Statistics Ligands Drugs & Drug Targets Visualize Visualize 3D Viewer Protein Feature View Human Gene View Pathway View Analyze Sequence & Structure Alignment Protein Symmetry Structure Quality Map Genomic Position to Protein PDB Statistics EPPIC Biological Assemblies Integrated Resources Third Party Tools Download Coordinates & Experimental Data Sequences Ligands FTP Archive & Services HTTPS Services Other Services Web Services Learn About Molecule of the Month Browse all Resources Educational Resources Curricula Guide to PDB Data News and Events More Contact Us Citing Us Policies Help Topics About RCSB PDB PDB History Team Members Advisory Committee News Publications Careers 168889 Biological Macromolecular Structures Enabling Breakthroughs in Research and Education Welcome Deposit Search Visualize Analyze Download Learn Deposit Options Prepare Data Validate Data Deposit Data Deposition Help Documentation PDBx/mmCIF Dictionary Resources Chemical Component Dictionary Biologically Interesting Molecule Reference Dictionary (BIRD) PDB Format Guide Search Options Basic Search Advanced Search Sequence Search Unreleased & New Entries Browse by Annotation Explore the Archive PDB Statistics Ligands Visualization Options Viewers 3D Structure Viewers Pathway View Sequence Protein Feature View Human Gene View Sequence & Structure Alignment Protein Symmetry Structure Quality Map Genomic Position to Protein PDB Statistics EPPIC Biological Assemblies Integrated Resources Third Party Tools Download Options Batch Download Coordinates & Experimental Data Sequences Ligands FTP Archive & Services HTTPS Services Web Services Overview Welcome A Structural View of Biology This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data. The RCSB PDB builds upon the data by creating tools and resources for research and education in molecular biology, structural biology, computational biology, and beyond. September Molecule of the Month SARS-CoV-2 RNA-dependent RNA Polymerase Deposition Preparation Tools Data Extraction pdb_extract : Extract and harvest data in PDBx/mmCIF format from structure determination programs SF-Tool : Convert structure factor files among various formats Small Molecules Ligand Expo : Search the Chemical Component Dictionary for the IDs of released ligands Data Format Conversion PDBML2CIF : Convert PDBML-format data into PDBx/mmCIF-format PointSuite : Generate symmetry records for macromolecular assemblies with point and helical symmetries MAXIT : Translate data between file formats and more Validation Services Validation reports contain an assessment of the quality of a structure and highlight specific concerns by considering the coordinates of the model, the experimental data and the fit between the two. Easily interpretable summary information that compares the quality of a model with that of other models in the archive will help users of PDB data to critically assess archived entries and to select the most appropriate structural models for their needs. These reports are developed using the recommendations of the wwPDB Validation Task Forces . Reports for released entries are available from Structure Summary pages. Validation reports for manuscript reviewers are created during annotation of deposited structures. Information and example Validation Reports (at wwpdb.org) . Check your X-ray, NMR, or EM structures before depositing (standalone server). Deposit 3D macromolecular structure data to the PDB Have non-atomic coordinates, multi-scale structures obtained through integrative/hybrid (I/H) methods? Deposit at PDB-Dev which is a prototype deposition and archiving system for structural models obtained through integrative/hybrid (I/H) methods. Questions about your deposition? Deposit FAQ Tutorials wwPDB Annotation Policies wwPDB Processing Procedures Basic Search From any page on the site, a Basic Search can be run by entering a search term in the top Search Bar. As you enter a term, you will see suggestions appearing in the dropdown menu that appears below the search bar. The suggestions are grouped by attribute name, indicating in the specific field or fields in which the search term was found. You can click on an item in the dropdown menu to see results matching only that particular attribute, or click the Search icon to see results matching multiple fields. Advanced Search The Advanced Search Query Builder tool allows you to construct complex boolean queries by specifying values for a wide range of structure attributes. Text-based queries can be combined with sequence and structure similarity searches. Search results can be returned at the structure, entity, or assembly level, and viewed in a variety of formats, for example, as a summary view, an images only gallery view, or in a Tabular Report format. Any query and its results can be further refined by selecting additional criteria from the ’Refinements’ panel. Go to Advanced Search Search by Sequences Search protein and nucleic acid sequences using the mmseqs2 method to find similar protein or nucleic acid chains in the PDB. The new Advanced Search Query Builder tool can be used to run sequence searches, and to combine the results with the other search criteria that are available. Read Tutorial Advanced Search - Sequence Search Search by Unreleased & Access New Entries The PDB archive is updated weekly in two phases Phase I: Every Saturday by 3:00 UTC, for every new entry, wwPDB website provides sequence(s) (amino acid or nucleotide) for each distinct polymer and, where appropriate, the InChI string(s) for each distinct ligand and the crystallization pH value(s) . Phase II: Every Wednesday by 00:00 UTC, all new and modified data entries will be updated at each of the wwPDB FTP sites. As of Tue Sep 15 2020 there are 168889 structures. Access new data entries this week Search unreleased entries Next data entry update in: Browse by Annotation PDB entries have been annotated by various ontologies and hierarchical classification schemes. Anatomical Therapeutic Chemical Classification System Biological Process CATH Cellular Component Enzyme Classification Genome Location Membrane Protein MeSH (Medical Subject Headings) Molecular Function SCOP Protein Symmetry Source Organism Start Browsing Explore the PDB Archive Organism Taxonomy Experimental Method Resolution (Å) Release Year Entity Polymer Type Enzyme Classification Membrane Protein Homo sapiens (49118) Mus musculus (7036) Escherichia coli (6107) synthetic construct (5058) Escherichia coli K-12 (3538) Rattus norvegicus (3212) Bos taurus (3044) Saccharomyces cerevisiae (2796) Saccharomyces cerevisiae S288C (1902) Others (39230) Eukaryota (91019) Bacteria (59044) Riboviria (8164) Archaea (5220) artificial sequences (5093) Duplodnaviria (2447) Varidnaviria (549) Monodnaviria (438) unidentified (228) Others (255) X-RAY DIFFRACTION (149649) SOLUTION NMR (13047) ELECTRON MICROSCOPY (5752) NEUTRON...